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Idebenone Skincare: What Are Antioxidants?

The term antioxidant is a buzzword used throughout the health and beauty industry. However, many people aren't quite clear on what antioxidants actually are and why they're so beneficial to your health. Antioxidants are a group of naturally occurring compounds that protect your cells from damage.

Your body makes some antioxidants on its own, but the vast majority of antioxidants you must get from the foods you eat or supplements.

Although, there is some indication that antioxidant supplements aren't as effective as getting antioxidants through your diet. Antioxidants are especially plentiful in fresh fruits and vegetables. They are important for the health of your entire body, not just your skin.

Antioxidants are used extensively in over-the-counter skincare products and cosmeceuticals. They are used topically to improve many cosmetic skin issues and are credited with having anti-aging and skin-protecting qualities.

Lipoic Acid

Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA), and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). ALA is made in animals normally and is essential for aerobic metabolism.

Oral lipoic acid (LA) is an over-the-counter supplement that has been investigated as an antioxidant, anti-inflammatory, and neuroprotective agent in MS. LA and its reduced form, dihydrolipoic acid (DHLA), are potent antioxidants with multiple modes of action. LA/DHLA can regenerate other antioxidants, such as glutathione, vitamin C, and vitamin E; serve as a ROS scavenger; repair oxidative damage, and chelate metallic ions involved in the oxidative injury. DHLA acts by restoring reduced levels of other antioxidants, such as glutathione, and by repairing oxidative damage.102–104 LA is absorbed from the diet and synthesized de novo; it readily converts intracellularly to DHLA. Both LA and DHLA are present in both extracellular and intracellular environments.

Vitamin C

Vitamin C is a vitamin found in various foods and sold as a dietary supplement. It is used to prevent and treat scurvy. Vitamin C is an essential nutrient involved in the repair of tissue and the enzymatic production of certain neurotransmitters

Vitamin C is a vital nutrient for health. It helps form and maintains bones, skin, and blood vessels. It is also an antioxidant.

Vitamin C occurs naturally in some foods, especially fruits and vegetables. Vitamin C supplements are also available.

Other names for vitamin C include L-ascorbic acid, ascorbic acid, and L-ascorbate.

In this article, learn more about why we need vitamin C, how much we need, and where to find it.

Why we need vitamin C

Vitamin C is water-soluble, and the body does not store it. To maintain adequate levels of vitamin C, people need to consume food that contains it every day.

The body needs vitamin C for various functions. Here are some of them:

  • It helps the body produce collagen, L-carnitine, and some neurotransmitters.
  • As an antioxidant, it helps remove unwanted substances known as reactive oxidative species (ROS) from the body.
  • It helps the body absorb iron.
  • It boosts the immune system.
  • It enhances wound healing.


ROS are substances such as free radicals that result from natural bodily processes, exposure to pollution, and other factors. They can lead to oxidative stress, which can, in turn, cause cell damage.

Vitamin C’s antioxidant activity may help reduce inflammation and lower the risk of developing various conditions, including some cancers.

The body needs vitamin C to produce collagen. This is the main component of connective tissue and makes up 1–2% of muscle tissue.


The benefits of vitamin C may include the following.

Wound healing

Vitamin C helps the body produce collagen and is present in skin, muscle, and other tissues.

People with a low intake of vitamin C may experience slower wound healing, as their bodies will be less able to produce collagen.

During times of recovery, healthcare professionals may recommend trusted Source supplements for people with low vitamin C levels.

Coenzyme Q10

Coenzyme Q, also known as ubiquinone, is a coenzyme family that is ubiquitous in animals and most bacteria. In humans, the most common form is Coenzyme Q₁₀ or ubiquinone-10

Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas. It is eaten in small amounts in meats and seafood. Coenzyme Q10 can also be made in a laboratory.

Coenzyme Q10 is most commonly used for conditions that affect the heart such as heart failure and fluid build-up in the body (congestive heart failure or CHF), chest pain (angina), and high blood pressure. It is also used for preventing migraine headaches, Parkinson's disease, and many other conditions.

How does it work?

Coenzyme Q10 is an important vitamin-like substance required for the proper function of many organs and chemical reactions in the body. It helps provide energy to cells. Coenzyme Q10 also seems to have antioxidant activity. People with certain diseases, such as heart failure, high blood pressure, gum disease, Parkinson's disease, blood infections, certain diseases of the muscles, and HIV infection, might have lower levels of coenzyme Q10.


Kinetin is a type of cytokinin, a class of plant hormones that promotes cell division. Kinetin was originally isolated by Miller and Skoog et al. as a compound from autoclaved herring sperm DNA that had cell division-promoting activity.

Kinetin is a cytokinin. Cytokinins are compounds that stimulate plants to grow. Kinetin occurs naturally in humans and is sometimes used to make medicine.

People use kinetin most often for aging skin, skin wrinkles from sun damage, and a skin condition that causes redness on the face (rosacea), but there is no good scientific evidence to support these uses.

How does it work?

Kinetin prevents green plant leaves from turning brown. There is some information that suggests kinetin might prevent age-related changes in human skin by protecting the DNA in skin cells from damage (antioxidant effects) and decreasing skin water loss.

Vitamin E

Vitamin E is a group of eight fat-soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitamin E, can cause nerve problems

Vitamin E is an antioxidant. It may help protect your cells from damage. This essential nutrient occurs naturally in many foods. It’s also available as a dietary supplement. Sometimes, it’s in processed foods. Vitamin E is fat-soluble. This means your body stores and uses it as needed.

Vitamin E is a vitamin that dissolves in fat. It is found in many foods including vegetable oils, cereals, meat, poultry, eggs, fruits, vegetables, and wheat germ oil. It is also available as a supplement.

Vitamin E is used for treating vitamin E deficiency, which is rare but can occur in people with certain genetic disorders and in very low-weight premature infants. Vitamin E is also used for many other conditions, but there is no good scientific evidence to support these other uses.

A type of vitamin E called vitamin E acetate is an ingredient in some vaping products. Using vaping products containing vitamin E acetate has been linked to serious lung injury.

How does it work?

Vitamin E is an important vitamin required for the proper function of many organs in the body. It is also an antioxidant. This means it helps to slow down processes that damage cells.


Idebenone is a drug that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimer's disease and other cognitive defects. This has been met with limited success. The Swiss company Santhera Pharmaceuticals has started to investigate it for the treatment of neuromuscular diseases.

Idebenone is a man-made product similar to coenzyme Q-10.

Idebenone is used for Alzheimer's disease, liver disease, and heart disease; as well as a number of inherited disorders including Leber's disease (an eye condition), mitochondrial encephalomyopathies (nerve and muscle disorders), and Friedreich's ataxia (a nervous system disorder that worsens over time, producing gait and speech problems, and eventually leading toward heart disease and diabetes).

Idebenone is used for Alzheimer's disease, Huntington’s disease, liver disease, and heart disease. It is also used for a number of inherited disorders including a condition that causes vision loss (Leber’s hereditary optic neuropathy), mitochondrial encephalomyopathies (nerve and muscle disorders), a type of muscular dystrophy called Duchenne muscular dystrophy, and Friedreich's ataxia (a nervous system disorder that worsens over time, producing gait and speech problems, and eventually leading toward heart disease and diabetes).

How does it work?

Idebenone seems to have antioxidant activity and appears to protect a wide variety of cells from oxidative damage.


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